Yildirim Cinar, An excellent. Mete Senyol, Kamber Duman, Blood viscosity and you may blood pressure: role off heat and hyperglycemia, American Diary from Blood circulation pressure, Regularity step one4, Procedure 5, , Users 433–438,
We planned a study to research the relations among blood pressure (BP), viscosity, and temperature in healthy subjects and among BP, viscosity, and how to hookup in Portland glucose in diabetics. With simple random sampling method, 53 healthy and 29 diabetes mellitus (DM) type II subjects were selected. Parameters were determined with capillary viscometer and glucometer at 22°C, 36.5°C, and 39.5°C in healthy subjects, and at 22°C on diabetic patients during OGTT with 75 g of glucose. Statistical evaluations of the data were made with regression analysis, Student t test, Spearman’s correlation, and analysis of variance. When temperature decreased from 36.5°C to 22°C, blood viscosity increased %. This increase resulted in a % decrease in blood flow rate. According to the Hagen-Poiseuille equation, the required BP increase for compensation of the resulting tissue ischemia was %. Also, a % decrease in erythrocyte deformability and % increase in plasma viscosity were seen. When temperature increased from 36.5° to 39.5°C, blood viscosity decreased %. This caused % decrease in blood flow rate, and % decrease in BP, according to the equation. Erythrocyte deformability increase of 9.92% and plasma viscosity decrease of 4.99% arose from the temperature rise. There is a correlation between total data for temperatures and viscosities (r = ?0.84, P
The purpose of our very own studies is to try to check out the relationship certainly one of temperature, glucose focus, and you can viscosity of blood and you can plasma, also to estimate their consequences towards the blood pressure level (BP) considering Hagen-Poiseuille’s hydrodynamics picture. If the human circulatory system is considered as a closed system, hemodynamic equilibrium can be determined according to Poiseuille’s equation through the pressure, viscosity, flow rate, velocity of blood, and vessel diameter. Viscosity can be defined as the resistance of fluids against flow. The resistance for blood circulation includes friction between the blood elements and between the vessel lumen and blood. To make a fluid flow, the application of energy is required. Therefore, the energy of the circulatory system is spent in correlation with the viscosity level of blood. Energy forms of the circulatory system are BP and blood flow velocity. The velocity (v) and pressure of blood flow can be determined with Poiseuille’s equation as v = 1/4?L (F1 ? F2) (a 2 ? r 2 ), and also BP rate (Q) can be expressed from the above equation as Q = ?a 4 /8 ?L (F1 ? F2), where ? is the viscosity of the fluid, F1 and F2 are the initial and the final cross sectional pressures of blood, L is the length, a is the radius of vessel, and r is the distance from the center of the vessel for a flowing particle. 1, 2 Thus, to keep the equilibrium of the equation constant in the circulatory system, BP will increase when viscosity increases. It has been revealed you to definitely ranging from % and % beliefs off hematocrit, most of the eleven% boost in hematocrit develops bloodstream viscosity because of the 20%. Within condition, centered on Poiseuille’s formula, blood flow rate decreases because of the %, that could bring about muscle ischemia. To keep this new circulatory system inside harmony (which is, keeping the latest circulate speed adequate and stopping tissues ischemia), a great 20% upsurge in BP otherwise 4.66% vasodilation is required. 3 However, the human being circulatory system is not an accurate finalized program, due to the fact blood viscosity should be altered to the consumption regarding dining or pills. 4–8 As well, the results off fat molecules as well as specific medications to the bloodstream viscosity and hemodynamics particularly BP had been said. Because atherosclerotic vessels don’t dilate sufficiently just like the a reaction to vasodilator medications, this has been suggested you to definitely enhanced blood viscosity can only be settled which have a great BP upsurge in instance things. 9–several Plus, brand new relationships certainly BP, horror, coagulation, blood flow velocity, and you can blood viscosity had been described through the beliefs off hemodynamics. 13, fourteen Bloodstream viscosity and you may blood pressure: part regarding temperature and you can hyperglycemia
